129872-88-4Relevant academic research and scientific papers
DIARYL-PURINE, AZAPURINES AND -DEAZAPURINES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR TREATMENT OF HIV
-
Page/Page column 33; 36, (2008/06/13)
This application concerns certain 2-phenylamino-6-aryl amino-, 6-aryloxy-, and 6- arylthio- purines, -azapurines and -deazapurines. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.
Direct C-Glycosylation of Guanine Analogues: The Synthesis and Antiviral Activity of Certain 7- and 9-Deazaguanine C-Nucleosides
Girgis, Nabih S.,Michael, Maged A.,Smee, Donald F.,Alaghamandan, Hassan A.,Robins, Roland K.,Cottam, Howard B.
, p. 2750 - 2755 (2007/10/02)
C-Glycosylation of two guanine analogues, 9-deaza- and 7-deazaguanine, has been achieved under Friedel-Crafts conditions, providing a direct synthetic route to 9-deazaguanosine (4; 2-amino-7-β-D-ribofuranosyl-5H-pyrrolopyrimidin-4(3H)-one) and 8-β-
