1299469-68-3

Basic information

• Product Name: N,N'-(3,7,13,17-tetraoxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-fluorobenzamide)
• Synonyms: N,N'-(3,7,13,17-tetraoxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-fluorobenzamide)
• CAS NO: 1299469-68-3
• Molecular Weight: 602.638
• Mol File: 1299469-68-3.mol

Chemical Properties

• CAS DataBase Reference: N,N'-(3,7,13,17-tetraoxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-fluorobenzamide)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(3,7,13,17-tetraoxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-fluorobenzamide)(1299469-68-3)
• EPA Substance Registry System: N,N'-(3,7,13,17-tetraoxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-fluorobenzamide)(1299469-68-3)

Safety Data

• Hazardous Substances Data: 1299469-68-3(Hazardous Substances Data)

Upstream product

• 456-22-4 4-Fluorobenzoic acid 
• 1299469-67-2 benzyl 3-(4-fluorobenzamido)propanoate 
• 440341-64-0 3-(4-fluorobenzamido)propanoic acid 
• 1227185-30-9 tert-butyl 3,3'-(propane-1,3-diylbis(azanediyl))bis(3-oxopropane-3,1-diyl)dicarbamate 

Downstream Products

• 1299469-65-0 N,N'-(3,7,13,17-tetrathioxo-4,8,12,16-tetraazanonadecane-1,19-diyl)bis-(4-hydroxybenzothioamide) 

Relevant articles and documents

Antiterminator-mediated unveiling of cryptic polythioamides in an anaerobic bacterium

Anti-Terminator: Rise of the Molecules: Overexpression of an antiterminator gene (nusG) in Clostridium cellulolyticum induced the biosynthesis of the novel antibiotic closthioamide and related thioamides. This is the first successful genetic engineering of an anaerobe to trigger a cryptic pathway. Furthermore, synthetic probes provide valuable insights into the biogenetic relationship of the rare thioamide metabolites. Copyright

CLOSTHIOAMIDES

This invention relates to the field of biologically active compounds and specifically to closthioamides, pharmaceutical compositions comprising these compounds, and their use as antibiotic, antifungal, and/or cytotoxic agent.