129954-34-3
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Basic information
- Product Name: Selank peptide
- Synonyms: Selank peptide;SelankAcetate
- CAS NO:129954-34-3
- Molecular Formula: C33H57N11O9
- Molecular Weight: 751.87
- EINECS: -0
- Product Categories: N/A
- Mol File: 129954-34-3.mol
- Article Data: 0
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Chemical Properties
- Melting Point: 134-136 °C
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: 1.53±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 3.43±0.20(Predicted)
- CAS DataBase Reference: Selank peptide(CAS DataBase Reference)
- NIST Chemistry Reference: Selank peptide(129954-34-3)
- EPA Substance Registry System: Selank peptide(129954-34-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 129954-34-3(Hazardous Substances Data)
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129954-34-3 Usage
Description
Selank is a synthetic derivative of the tetrapeptide tuftsin that contains a proline-glycine-proline sequence at the C-terminus and has anxiolytic and anti-inflammatory activities. It increases the amplitude and discharge rate of inhibitory postsynaptic currents of neurons in the rat hippocampal CA1 region when used at a concentration of 1 μM. It decreases the level of affective responses and the number of erroneous escape attempts in rats in an acute stress situation, increases orientational-investigative responses of rats in an unfamiliar situation, and reduces the time mice spend immobile in the forced swim test. It increases locomotor activity of high-anxiety Balb/c, but not C57Bl/6, mice in the open field test. Selank (0.01 mg/kg) decreases verticalization induced by apomorphine in mice. It also decreases expression of the inflammation-related genes Il2rg and Xcr1 in mouse spleen after 90 minutes when administered at a dose of 100 μg/kg.Check Digit Verification of cas no
The CAS Registry Mumber 129954-34-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,9,5 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.Calculate Digit Verification of CAS Registry Number 129954-34:
(8*1)+(7*2)+(6*9)+(5*9)+(4*5)+(3*4)+(2*3)+(1*4)=163
163 % 10 = 3
So 129954-34-3 is a valid CAS Registry Number.
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Selank peptide
