130064-30-1

Basic information

• Product Name: 2-(4-(2-piperidinoethoxy)phenyl)-3-(4-hydroxyphenyl)-2H-1-benzopyran
• Synonyms: 2-(4-(2-piperidinoethoxy)phenyl)-3-(4-hydroxyphenyl)-2H-1-benzopyran
• CAS NO: 130064-30-1
• Molecular Formula: C₂₈H₂₉NO₃
• Molecular Weight: 0
• Mol File: 130064-30-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 603.2°C at 760 mmHg
• Flash Point: 318.6°C
• Appearance: /
• Density: 1.189g/cm³
• Vapor Pressure: 3.8E-15mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 2-(4-(2-piperidinoethoxy)phenyl)-3-(4-hydroxyphenyl)-2H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(2-piperidinoethoxy)phenyl)-3-(4-hydroxyphenyl)-2H-1-benzopyran(130064-30-1)
• EPA Substance Registry System: 2-(4-(2-piperidinoethoxy)phenyl)-3-(4-hydroxyphenyl)-2H-1-benzopyran(130064-30-1)

Safety Data

• Hazardous Substances Data: 130064-30-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C28H29NO3/c30-24-12-8-21(9-13-24)26-20-23-6-2-3-7-27(23)32-28(26)22-10-14-25(15-11-22)31-19-18-29-16-4-1-5-17-29/h2-3,6-15,20,28,30H,1,4-5,16-19H2

Upstream product

• 130064-28-7 2-(4-hydroxyphenyl)-3-<4-<(tetrahydropyran-2-yl)oxy>phenyl>-2H-1-benzopyran 
• 79744-47-1 1-(2-hydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 109561-92-4 1-(2-hydroxyphenyl)-2-(4-hydroxyphenyl)ethanone 
• 1932-03-2 2-(piperidin-4-yl)ethyl chloride 
• 123-08-0 4-hydroxy-benzaldehyde 
• 2008-75-5 N-chloroethylpiperidine hydrochloride 
• 130064-29-8 1-[2-(4-{3-[4-(Tetrahydro-pyran-2-yloxy)-phenyl]-2H-chromen-2-yl}-phenoxy)-ethyl]-piperidine 

Relevant articles and documents

Synthesis and post-coital contraceptive activity of a new series of substituted 2,3-diaryI-2H-1-benzopyrans

A series of substituted 2,3-diaryl-2H-1-benzopyrans have been synthesized and screened for their post-coital contraceptive activity in rats. Most of the compounds showed 100% inhibition in a single day schedule at a dose level of 1.0 mg/kg. Compound 32 was found to be the most active with a minimum effective dose (MED) of 0.2 mg/kg in single day testing. Further, it also showed high antiestrogenic activity and is devoid of any agonistic activity.

Structure-Activity Relationship of Antiestrogens. Phenolic Analogues of 2,3-Diaryl-2H-1-benzopyrans

Phenolic analogues of 2--3-phenyl-2H-1-benzopyran (1), a novel antiestrogen, were synthesized and evaluated for their structure-activity relationship.Incorporation of OH at position 7 was found to improve receptor affinity of