79744-47-1

Upstream product

• 74384-21-7 phenyl 2-(4-(methoxy)phenyl)acetate 
• 611-20-1 salicylonitrile 
• 824-94-2 p-methoxybenzyl chloride 
• 104-47-2 p-methoxybenzylnitrile 
• 1276694-79-1 p-methoxyphenylacetic acid 2-(methoxycarbonyl)phenyl ester 
• 26151-95-1 4-hydroxy-3-(4-methoxyphenyl)-2H-chromen-2-one 
• 606-45-1 2-methoxybenzoic acid methyl ester 
• 142751-38-0 Dimethyl-thiocarbamic acid O-{3-hydroxy-4-[2-(4-methoxy-phenyl)-acetyl]-phenyl} ester 
• 487-49-0 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone 
• 142751-42-6 Dimethyl-thiocarbamic acid S-{3-hydroxy-4-[2-(4-methoxy-phenyl)-acetyl]-phenyl} ester 

Downstream Products

• 1621-58-5 3-(4-methoxyphenyl)-4H-chromen-4-one 
• 1027428-82-5 1-(2-hydroxyphenyl)-2-(4-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one 
• 1459244-07-5 C₁₆H₁₃F₃O₅S 
• 71126-50-6 (3Z)-3-(4-methoxyphenylmethylidene)-2-benzofuran-1(3H)-one 
• 130064-29-8 1-[2-(4-{3-[4-(Tetrahydro-pyran-2-yloxy)-phenyl]-2H-chromen-2-yl}-phenoxy)-ethyl]-piperidine 
• 130064-23-2 1-(2-hydroxyphenyl)-2-<4-<(tetrahydropyran-2-yl)oxy>phenyl>-3-(4-hydroxyphenyl)prop-2-en-1-one 
• 130064-30-1 2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-[4-hydroxyphenyl]-2H-1-benzopyran 
• 130064-28-7 2-(4-hydroxyphenyl)-3-<4-<(tetrahydropyran-2-yl)oxy>phenyl>-2H-1-benzopyran 
• 130064-22-1 2,3-bis(hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one 
• 130064-19-6 1-(2-hydroxyphenyl)-2-<4-<(tetrahydropyran-2-yl)oxy>phenyl>ethanone 
• 145917-96-0 3-(4-methoxyphenyl)-2H-chromene 
• 105705-48-4 3-(4-methoxyphenyl)chroman-4-one 
• 157173-60-9 1-(2-{4-[3-(4-Methoxy-phenyl)-2H-chromen-2-yl]-phenoxy}-ethyl)-piperidine 
• 109561-92-4 1-(2-hydroxyphenyl)-2-(4-hydroxyphenyl)ethanone 

Relevant academic research and scientific papers

Microwave-assisted efficient synthesis of 2-hydroxydeoxybenzoins from the alkali degradation of readily prepared 3-aryl-4-.hydroxycoumarins in water

This paper describes an operationally simple, green and efficient approach for the synthesis of 2-hydroxydeoxybenzoins bearing diverse substituents from the microwave-assisted alkali degradation of 3-aryl- 4-hydroxycoumarins in water. The latter compounds

3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators

Following the recent identification of the naturally occurring 3-ylidene-4,5-dihydrophthalide ligustilide and its oxidation product dehydroligustilide as novel TRPA1 modulators, a series of seventeen 3-ylidenephthalides was synthesized and tested on TRPA1 and TRPM8 channels. Most of these compounds acted as strong modulators of the two channel types with EC50 and/or IC50 values distinctly lower than those of the reference compounds.

Inhibitors of acyl CoA:cholesterol acyltransferase

Conformational restriction of previously disclosed acyclic diphenylethyl)diphenylacetamides led to the discovery of several potent inhibitors of acyl CoA:cholesterol acyltransferase (ACAT). cis-[2-(4- Hydroxyphenyl)-1-indanyl]diphenylacetamide (4a) was the most potent ACAT inhibitor identified (IC50 = 0.04 μM in an in vitro rat hepatic microsomal ACAT assay, ED50 = 0.72 mg/kg/day in cholesterol-fed hamsters).

New procedures for the preparation of isoflavones with unsubstituted ring A

Isoflavones with unsubstituted ring A have been synthesized either by the ring closure of 2-hydroxydeoxybenzoins or by the dehydroxylation of 7-hydroxyisoflavones. 7-Mercaptoisoflavones have also been prepared.

Structure-Activity Relationship of Antiestrogens. Phenolic Analogues of 2,3-Diaryl-2H-1-benzopyrans

Phenolic analogues of 2--3-phenyl-2H-1-benzopyran (1), a novel antiestrogen, were synthesized and evaluated for their structure-activity relationship.Incorporation of OH at position 7 was found to improve receptor affinity of