1300698-74-1

Usage

Functional groups

Two difluoroethyl groups and one difluoroacetate group

Physical state

Liquid

Boiling point

92-94°C

Melting point

-41°C

Density

1.3 g/cm3

Solubility

Soluble in organic solvents such as ethanol, ether, and chloroform

Reactivity

High reactivity

Uses

Building block in the synthesis of other organic compounds, reagent in organic synthesis, production of pharmaceuticals and agrochemicals, and key intermediate in the manufacturing process of several industrial chemicals.

Upstream product

• 354-24-5 chlordifluoroacetyl chloride 
• 2925-22-6 2,2-difluoroacetyl fluoride 

Relevant academic research and scientific papers

Method for Producing Difluoroacetyl Chloride

A production method of difluoroacetyl chloride according to the present invention includes a chlorination step of bringing a raw material containing at least either a 1-alkoxy-1,1,2,2-tetrafluoroethane or difluoroacetyl chloride into contact with calcium chloride at a reaction enabling temperature. A production method of 2,2-difluoroethyl alcohol according to the present invention includes a catalytic reduction step of causing catalytic reduction of the difluoroacetyl chloride obtained by the above production method. By these methods, the difluoroacetyl fluoride can be efficiently converted to the difluoroacetyl chloride and to the 2,2-difluoroethyl alcohol.

Production of Difluoroethanol

Difluoroethanol is produced by hydrogenation, in the presence of an effective amount of a catalyst containing at least one element of Group VIII of the Periodic Table deposited onto a solid, acidic mineral support, of an acetyl halide having the following formula (I), in which formula X is a halogen atom other than a fluorine atom: