1300727-65-4Relevant academic research and scientific papers
Transamidation and Decarbonylation of N-Phthaloyl-Amino Acid Amides Enabled by Palladium-Catalyzed Selective C–N Bond Cleavage
Zhang, Hao-Yu,Tao, Xuan-Wen,Yi, Li-Na,Zhao, Zhi-Gang,Yang, Qiang
, p. 231 - 242 (2022/01/11)
Amides are important functional synthons that have been widely used in the construction of peptides, natural products, and drugs. The C–N bond cleavage provides the direct method for amide conversion. However, amides, especially secondary amides, tend to
Catalyst and solvent-free amidation of inactive esters of N-protected amino acids
Nadimpally, Krishna Chaitanya,Thalluri, Kishore,Palakurthy, Nani Babu,Saha, Abhijit,Mandal, Bhubaneswar
, p. 2579 - 2582 (2011/06/21)
A catalyst free procedure for the preparation of amides from inactive esters of N-protected amino acids and various amines is demonstrated under mild reaction conditions. Our effort to recover excess amine and generated alcohol is an approach towards environment friendly and cost effective synthesis under easy operational conditions.
