1300743-75-2Relevant academic research and scientific papers
Fast, ligand- and solvent-free copper-catalyzed click reactions in a ball mill
Thorwirth, Rico,Stolle, Achim,Ondruschka, Bernd,Wild, Andreas,Schubert, Ulrich S.
supporting information; experimental part, p. 4370 - 4372 (2011/06/22)
A new, ligand- and solvent-free method for the Huisgen 1,3-dipolar cycloaddition (click reaction) was developed using a planetary ball mill. Besides various alkynes and azides, a propargyl functionalized polymer was converted by mill clicking. Moreover, it was possible to carry out a click polymerization in a ball mill.
