1300747-73-2Relevant academic research and scientific papers
Evaluation of thiazole containing biaryl analogs as diacylglycerol acyltransferase 1 (DGAT1) inhibitors
Kadam, Kishorkumar S.,Jadhav, Ravindra D.,Kandre, Shivaji,Guha, Tandra,Reddy, M. Mahesh Kumar,Brahma, Manoja K.,Deshmukh, Nitin J.,Dixit, Amol,Doshi, Lalit,Srinivasan, Shaila,Devle, Jayendra,Damre, Anagha,Nemmani, Kumar V. S.,Gupte, Amol,Sharma, Rajiv
, p. 337 - 347 (2013)
Biphenyl carboxylic acids, exemplified by compound 5, are known potent inhibitors of diacylglycerol acyltransferase, DGAT1, an enzyme involved in the final committed step of triglyceride biosynthesis. We have synthesized and evaluated 2-phenylthiazole, 4-
HETEROARYL COMPOUNDS AS DGAT-1 1NHIBITORS
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Page/Page column 41, (2011/06/11)
The present invention relates to novel heteroaryl compounds, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or disorders mediated by Diacylglycerol acyltransferase (DGAT) enzyme, particularly DGAT- 1.
