1301127-20-7

Basic information

• Product Name: diethyl (S)-3-isopropyl-4-phenyl-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide
• Synonyms: diethyl (S)-3-isopropyl-4-phenyl-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide
• CAS NO: 1301127-20-7
• Molecular Weight: 349.384
• Mol File: 1301127-20-7.mol

Chemical Properties

• CAS DataBase Reference: diethyl (S)-3-isopropyl-4-phenyl-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (S)-3-isopropyl-4-phenyl-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide(1301127-20-7)
• EPA Substance Registry System: diethyl (S)-3-isopropyl-4-phenyl-4,5-dihydroisoxazole-5,5-dicarboxylate 2-oxide(1301127-20-7)

Safety Data

• Hazardous Substances Data: 1301127-20-7(Hazardous Substances Data)

Upstream product

• 113334-89-7 C₁₁H₁₃NO₂ 
• 685-87-0 Diethyl 2-bromomalonate 

Relevant articles and documents

Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions

Catalytic asymmetric syntheses of various isoxazoline-N-oxides have been accomplished by asymmetric phase-transfer conjugate addition of bromomalonate to nitroolefins and subsequent ring-closing O-alkylation.

Catalytic asymmetric synthesis of isoxazoline-n-oxides through conjugate additioncyclization under phase-transfer conditions

Catalytic asymmetric synthesis of various isoxazoline-N-oxides having a tetrasubstituted carbon has been accomplished by asymmetric phase-transfer conjugate addition of bromomalonate to nitroolefins and subsequent ringclosing O-alkylation. The obtained isoxazoline-N-oxide was readily converted to the corresponding oxime, isoxazoline, and lactam without loss of optical purity.