1301634-87-6

Basic information

• Product Name: C₂₈H₃₈BrN₃O₆
• Synonyms: C₂₈H₃₈BrN₃O₆
• CAS NO: 1301634-87-6
• Molecular Weight: 592.53
• Mol File: 1301634-87-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₈BrN₃O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₈BrN₃O₆(1301634-87-6)
• EPA Substance Registry System: C₂₈H₃₈BrN₃O₆(1301634-87-6)

Safety Data

• Hazardous Substances Data: 1301634-87-6(Hazardous Substances Data)

Upstream product

• 1255212-86-2 (2S,5S,6S)-tert-Butyl 2-(tert-butyldimethylsilyloxy)-4-(1-(4-methoxybenzyloxy)propan-2-ylamino)-3-methylbutyl(methyl)carbamate 
• 1301634-79-6 C₃₄H₅₃BrClN₃O₆Si 
• 78686-86-9 5-bromo-2-chloro-pyridine-3-carbonyl chloride 

Downstream Products

• 1301634-94-5 C₃₈H₄₀BrN₃O₆ 

Relevant articles and documents

Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via SNAr cycloetherification

We have implemented an aldol-based "build/couple/pair" (B/C/P) strategy for the synthesis of stereochemically diverse 8-membered lactam and sultam scaffolds via SNAr cycloetherification. Each scaffold contains two handles, an amine and aryl bromide, for solid-phase diversification via N-capping and Pd-mediated cross coupling. A sparse matrix design strategy that achieves the dual objective of controlling physicochemical properties and selecting diverse library members was implemented. The production of two 8000-membered libraries is discussed including a full analysis of library purity and property distribution. Library diversity was evaluated in comparison to the Molecular Library Small Molecule Repository (MLSMR) through the use of a multifusion similarity (MFS) map and principal component analysis (PCA).