1255212-86-2Relevant academic research and scientific papers
COMPOUNDS FOR INDUCING PROLIFERATION AND DIFFERENTIATION OF CELLS, AND METHODS OF USE THEREOF
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Paragraph 0334; 0344; 0345, (2016/02/24)
The present invention provides methods of inducing proliferation of and/or differentiating cells comprising contacting cells with compounds within the methods of the invention. The present invention further provides cells obtainable by the methods of the
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: Discovery of macrocyclic histone deacetylase inhibitors
Marcaurelle, Lisa A.,Comer, Eamon,Dandapani, Sivaraman,Duvall, Jeremy R.,Gerard, Baudouin,Kesavan, Sarathy,Lee, Maurice D.,Liu, Haibo,Lowe, Jason T.,Marie, Jean-Charles,Mulrooney, Carol A.,Pandya, Bhaumik A.,Rowley, Ann,Ryba, Troy D.,Suh, Byung-Chul,Wei, Jingqiang,Young, Damian W.,Akella, Lakshmi B.,Ross, Nathan T.,Zhang, Yan-Ling,Fass, Daniel M.,Reis, Surya A.,Zhao, Wen-Ning,Haggarty, Stephen J.,Palmer, Michelle,Foley, Michael A.
, p. 16962 - 16976 (2011/02/17)
An aldol-based build/couple/pair (B/C/P) strategy was applied to generate a collection of stereochemically and skeletally diverse small molecules. In the build phase, a series of asymmetric syn- and anti-aldol reactions were performed to produce four ster
