1301669-22-6Relevant academic research and scientific papers
Asymmetric mannich-type reactions of fluorinated ketoesters with binaphthyl-modified thiourea catalysts
Kang, Young Ku,Yoon, Sung Je,Kim, Dae Young
experimental part, p. 1195 - 1200 (2011/11/06)
The catalytic enantioselective Mannich-type reaction promoted by chiral binaphthyl-modified bifunctional organocatalysts is described. The treatment of α-fluoro-β-ketoesters with N-Boc imines under mild reaction conditions afforded the corresponding β-aminated α-fluoro-β- ketoesters with excellent enantioselectivities (up to 98% ee).
Catalytic asymmetric Mannich-type reactions of fluorinated ketoesters with N-Boc aldimines in the presence of chiral palladium complexes
Kang, Young Ku,Kim, Dae Young
experimental part, p. 2356 - 2358 (2011/05/16)
The catalytic enantioselective Mannich reaction promoted by chiral palladium complexes is described. The treatment of α-fluoro-β- ketoesters with N-Boc-aldimines under mild reaction conditions afforded the corresponding β-aminated α-fluoro-β-ketoesters wi
