130179-66-7

Upstream product

• 130159-64-7 (2R,3R,4R,5S)-5-Phenyl-3-((3R,7aS)-2-phenyl-hexahydro-pyrrolo[1,2-c]imidazol-3-yl)-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 130159-77-2 (2R,3R,4R,5S)-3-Dimethoxymethyl-5-phenyl-1-(toluene-4-sulfonyl)-pyrrolidine-2,4-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

ASYMMETRIC 1,3-DIPOLAR CYCLOADDITIONS OF AZOMETHINE YLIDES WITH A CHIRAL ELECTRON-DEFICIENT OLEFINIC DIPOLAROPHILE

The first example of efficient asymmetric 1,3-dipolar cycloadditions of azomethine ylides is presented, where reactive N-metalated azomethine ylides and the α,β-unsaturated ester with a chiral perhydropyrroloimidazol-3-yl moiety at the β-position h

Asymmetric cycloaddition of N-metalated azomethine ylides with the optically active α,β-unsaturated esters derived from α-amino acids

α,β-Unsaturated esters bearing a chiral oxazolidine or perhydropyrrolo[1,2-c]imidazole auxiliary at the β-position have been prepared and applied to the cycloadditions with N-metalated azomethine ylides derived from a-(benzylideneamino) esters. These reac