13019-38-0Relevant academic research and scientific papers
A convenient synthesis of 3-aryl-δ-lactones
Rosen, Jonathan D.,Nelson, Todd D.,Huffman, Mark A.,McNamara, James M.
, p. 365 - 368 (2003)
Various (±)-3-aryl-δ-lactones have been prepared from the corresponding arylacetic acids. The lithium dianion of the acid is alkylated with 1-bromo-3-chloropropane and the unpurified product is cyclized with DBU in typically ca. 80% yield over both steps.
