130198-05-9Relevant articles and documents
Preparation method of venlafaxine hydrochloride intermediate
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Paragraph 0032-0067, (2021/01/11)
The invention belongs to the technical field of organic synthesis, and relates to a preparation method of a venlafaxine hydrochloride intermediate, which comprises the following steps: heating, quenching, extracting, concentrating and salifying. A venlafaxine impurity C synthesized by the method is high in yield, good in purity, safe in reaction, simple to operate, free of special requirements onequipment and suitable for industrial production.
DERIVATIVES OF (-)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME
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, (2015/11/23)
Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
PROCESS FOR THE PREPARATION OF HIGHLY PURE 1-[2-DIMETHYLAMINO-(4-METHOXYPHENYL) ETHYL]CYCLOHEXANOL HYDROCHLORIDE
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Page/Page column 20; 21, (2010/11/27)
The invention encompasses processes for the preparation of highly pure venlafaxine hydrochloride, l-[2-dimethylamino-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride as well as intermediates thereof.