130202-78-7

Basic information

• Product Name: N-Methyl-N-(β-hydroxy-β-phenyl)-ethyl-3-phenylglycidamide
• Synonyms: N-Methyl-N-(β-hydroxy-β-phenyl)-ethyl-3-phenylglycidamide
• CAS NO: 130202-78-7
• Molecular Weight: 297.354
• Mol File: 130202-78-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-Methyl-N-(β-hydroxy-β-phenyl)-ethyl-3-phenylglycidamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-N-(β-hydroxy-β-phenyl)-ethyl-3-phenylglycidamide(130202-78-7)
• EPA Substance Registry System: N-Methyl-N-(β-hydroxy-β-phenyl)-ethyl-3-phenylglycidamide(130202-78-7)

Safety Data

• Hazardous Substances Data: 130202-78-7(Hazardous Substances Data)

Upstream product

• 68579-60-2 2-(methylamino)-1-phenylethanol 
• 132490-26-7 (2R,3S)-phenyl 3-phenyloxirane-2-carboxylate 
• 19190-80-8 methyl 3-Phenylglycidate 
• 79898-19-4 (2R,3S)-3-phenyloxiranecarboxylic acid 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 104196-23-8 (2S,3S)-2,3-epoxy-3-phenyl-1-propanol 
• 122743-18-4 methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate 
• 5411-12-1 trans-(2S,3R)-epoxy-1,3-diphenylpropan-1-one 
• 190771-98-3 (2R,3S)-2,3-Dihydroxy-N-<(2'RS)-2'-hydroxy-2'-phenylethyl>-N-methylpropanamide 
• 115794-67-7 methyl (2R,3S)-3-phenylglycidate 

Downstream Products

• 103541-16-8 (-)-dehydroclausenamide 
• 103541-16-8 (-)-dehydroclausenamide 
• 130202-81-2 7-O-tosylneoclausenamide 
• 109905-95-5 (±)-(3R,4S,5S,6R)-clausenamide 
• 130273-47-1 (3R,4S,5R)-neoclausenamidone 
• 130273-48-2 (3R,4S,5S)-clausenamidone 
• 130202-79-8 (2R,3S)-2,3-Epoxy-N-methyl-N-phenacyl-3-phenylpropionamide 

Relevant articles and documents

New procedures for the Julia-Colonna asymmetric epoxidation: Synthesis of (+)-clausenamide

The oxidation of chalcone 1 to optically active epoxide 2 [a precursor of (+)-clausenamide (+)-3] may be effected using a 15-mer or 20-mer of L-leucine bound to a PEG based support; poly-L-leucines of this type may be used as immobilised catalysts in a fixed-bed reactor.

Process for the preparation of clausenamide and neoclausenamide, and derivatives thereof

A process for the preparation of compound of the formula STR1 in which R1 --represents STR2 and R2 --represents hydrogen, fluorine, chlorine or bromine. Comprising cyclizing compounds of the formula STR3 and, in a further step, eithe