130224-39-4

Basic information

• Product Name: 5-amino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxamide
• Synonyms: 5-amino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxamide
• CAS NO: 130224-39-4
• Molecular Weight: 248.308
• Mol File: 130224-39-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-amino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxamide(130224-39-4)
• EPA Substance Registry System: 5-amino-3-methylsulfanyl-1-phenyl-1H-pyrazole-4-carboxamide(130224-39-4)

Safety Data

• Hazardous Substances Data: 130224-39-4(Hazardous Substances Data)

Upstream product

• 59334-11-1 5-amino-3-(methylsulfanyl)-1-phenyl-1H-pyrazole-4-carbonitrile 
• 17823-69-7 2-cyano-3,3-bis(methylthio)acrylamide 
• 100-63-0 phenylhydrazine 

Downstream Products

• 130224-59-8 4-hydroxy-3,6-bis(methylthio)-1-phenylpyrazolo<3,4-d>pyrimidine 
• 1257081-68-7 6-(2-chloroethyl)-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-64-3 6-(2-methoxyphenyl)-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-67-6 6-chloromethyl-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-75-6 6-ethyl-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-62-1 6-(2-hydroxyphenyl)-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-53-0 3-methylsulfanyl-1,6-diphenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-58-5 3-methylsulfanyl-6-(3-nitrophenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-63-2 3-methylsulfanyl-6-(3-nitrophenyl)-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-55-2 6-(2-chlorophenyl)-3-methylsulfanyl-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-60-9 6-(4-chlorophenyl)-3-methylsulfanyl-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-56-3 6-(4-chlorophenyl)-3-methylsulfanyl-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 1257081-66-5 3-methylsulfanyl-1-phenyl-6-(2-thienyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one 
• 91974-70-8 4-hydroxy-3-methylthio-1-phenylpyrazolo<3,4-d>pyrimidine 

Relevant articles and documents

Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4- d]pyrimidin-4-one inhibitors of cyclin-dependent kinases

Using a high-throughput screening strategy, a series of 1-aryl-4,5-dihydro-1H-pyrazolo[3,4-d]-pyrimidin-4-ones was identified that inhibit the cyclin-dependent kinase (CDK) 4/cyclin D1 complex-mediated phosphorylation of a protein substrate with IC50