130234-74-1

Basic information

• Product Name: N-(5-chloropyridin-2-yl)-2-hydroxybenzamide
• Synonyms: N-(5-chloropyridin-2-yl)-2-hydroxybenzamide;N-(5-chloro-2-pyridinyl)-2-hydroxybenzamide
• CAS NO: 130234-74-1
• Molecular Formula: C₁₂H₉ClN₂O₂
• Molecular Weight: 249
• Mol File: 130234-74-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(5-chloropyridin-2-yl)-2-hydroxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-chloropyridin-2-yl)-2-hydroxybenzamide(130234-74-1)
• EPA Substance Registry System: N-(5-chloropyridin-2-yl)-2-hydroxybenzamide(130234-74-1)

Safety Data

• Hazardous Substances Data: 130234-74-1(Hazardous Substances Data)

Upstream product

• 280771-69-9 2-acetoxy-N-(5-chloropyridin-2-yl)benzamide 
• 1072-98-6 5-chloro-2-pyridylamine 
• 118-55-8 phenyl Salicylate 

Downstream Products

• 280772-25-0 N-(5-chloropyridin-2-yl)-2-(1-tert-butoxycarbonylpiperidin-4-ylmethoxy)benzamide 

Relevant articles and documents

Antimycobacterial N-pyridinylsalicylamides, isosters of salicylamides

The series of derivatives of substituted N-pyridinylsalicylamides were synthesized. The compounds were evaluated for in vitro antimycobacterial activity against Mycobacterium avium and two strains of Mycobacterium kansasii. In the quantitative structure activity relationships analysis (QSAR), the Free-Wilson and Hansch approaches were used but the analysis was not significant. (The standard deviations of regression coefficients were greater than the values of the coefficients). The molecules were separated the heterocyclic and salicyl moiety in the molecules, and the study of influences of substituents on salicyl moiety was used, as well. 5-Chloro-pyridin-2-yl, and the substitution of the salicyl moiety by chlorine in position 4 or 5 had the strongest influence on the increase in antimycobacterial activity.

Salicylanilide and its heterocyclic analogues. A comparative study of their antimicrobial activity

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