130252-76-5

Upstream product

• 89807-39-6 1-(2-hydroxy-5-methylphenyl)-3-(N,N-dimethylamino)propenone 
• 127820-39-7 tris(4-chlorophenyl)sulfonium trifluoromethanesulfonate 
• 14166-16-6 2-(4-chlorophenyl)-6-methylchroman-4-one 

Relevant academic research and scientific papers

Oxidative 1,2-aryl rearrangement in flavanones using thallium(III) p-tolylsulphonate (TTS): A new useful route to isoflavones

Oxidation of flavanones using thallium(III) p-tolylsulphonate (prepared in situ by the reaction of thallium(III) acetate and p-toluene sulphonic acid) in propionitrile leads to 1,2-aryl shift providing a new useful route to the synthesis of isoflavones.

Arylation of ortho-Hydroxyarylenaminones by Sulfonium Salts and Arenesulfonyl Chlorides: An Access to Isoflavones

Herein we disclose three new methods for the straightforward and efficient synthesis of 3-arylchromones following the arylation of ortho-hydroxyarylenaminones by vast diversities of bench-stable and easy-to-use sulfonium salts and arenesulfonyl chlorides.

Hypervalent Iodine Oxidation of Flawanones: Convenient and Useful Syntheses of Flavones and IsoFlavones

Hypervalent iodine oxidation of flavanones (1a-g) under a variety of conditions, offering convenient and valuable routes to the syntheses of flavones (2a-g) and isoflavones (3a-g), is described.The course of these oxidation reactions is greatly influenced by the reaction conditions and it is possible to select appropriate conditions for following a desired route (2/3).The mechanistic rationale for these transformations is also discussed.

Oxidation of Flavanones using Thallium(III) Salts: A New Route for the Synthesis of Flavones and Isoflavones

When treated with thallium(III) acetate in acetic acid or acetonitrile, flavanones undergo facile dehydrogenation to afford flavones whereas, upon treatment with thallium(III) toluene-p-sulfonate or thallium(III) nitrate in propionitrile or acetonitrile, respectively, they undergo oxidative 2,3-aryl migration to give isoflavones in high yield.