130252-82-3

Upstream product

• 121289-23-4 p-methoxybenzyloxyacetaldehyde 
• 13291-18-4 isopropenylmagnesium bromide 
• 824-94-2 p-methoxybenzyl chloride 
• 207120-79-4 1-methoxy-4-(3-methyl-but-2-enyloxymethyl)-benzene 
• 556-82-1 3-methyl-2-buten-1-ol 
• 870474-22-9 3-{[(4-methoxyphenyl)methoxy]methyl}-2,2-dimethyloxirane 

Downstream Products

• 130252-83-4 (2R,3S)-3,4-epoxy-1-(4-methoxyphenyl)methoxy-3-methyl-2-butanol 
• 130252-83-4 (S)-2-(4-Methoxy-benzyloxy)-1-((R)-2-methyl-oxiranyl)-ethanol 
• 145369-57-9 1-p-methoxybenzyloxy-3-methylbut-3-en-2-one 
• 130252-84-5 (2R,3S)-3,4-epoxy-1-(4-methoxyphenyl)methoxy-3-methylbutan-2-yl 3-methoxy-5-methyl-1-naphthoate 

Relevant academic research and scientific papers

Total synthesis of milbemycins: A synthesis of (6R)-6-hydroxy-3,4- dihydromilbemycin E

Following studies using benzyloxymethyl isopropenyl ketone 5 and ethyl 3-(3-furyl)-3-oxopropanoate 6, Robinson reactions between aryloxymethyl isopropenyl ketones 19 and 5 and ethyl 3-(2-trimethylsilyl-3-furyl)-3- oxopropanoate 20 were found to be stereos

Synthetic studies towards carzinophilin: Synthesis and ammonium hydroxide-induced rearrangement of the epoxi-acid fragment

An efficient synthesis of the epoxide-containing fragment 4 of carzinophilin has been completed. Intramolecular acyl transfer of a related epoxide afforded amide 16. Comparison by 1H NMR of 4 and 16 with authentic natural product provides further evidence for structural revision of carzinophilin.