130256-49-4

Upstream product

• 50409-12-6 cis,cis-1,3,5-trihydroxycyclohexane 
• 130256-37-0 (1S,5R)-3-Benzyloxymethyl-7-methylene-2,4-dioxa-bicyclo[3.3.1]nonane 
• 130256-40-5 (R)-5-benzyloxymethyl-2-cyclohexenone 
• 130256-38-1 cis-5-benzyloxymethyl-1,3-diacetoxycyclohexane 
• 130256-39-2 Acetic acid (1S,3S,5R)-3-benzyloxymethyl-5-hydroxy-cyclohexyl ester 
• 95205-55-3 (1S,5R,7R)-3-Benzyloxymethyl-2,4-dioxa-bicyclo[3.3.1]nonan-7-ol 
• 130323-27-2 (1S,5R,7R)-3-Hydroxymethyl-2,4-dioxa-bicyclo[3.3.1]nonan-7-ol 
• 50409-13-7 2,5,11-trioxatricyclo[4.3.1.14,8 ] undecan-3-one 
• 130256-42-7 (3R,5R)-5-Benzyloxymethyl-3-methyl-2-phenylselanyl-cyclohexanone 
• 917-54-4 methyllithium 
• 130256-48-3 5(S)-benzyloxymethyl-2-cyclohexenone 

Relevant academic research and scientific papers

Enantioselective C-C bond activation of allenyl cyclobutanes: Access to cyclohexenones with quaternary stereogenic centers

(Chemical Equation Presented) Chiral rhodium(I) complexes activate allenyl tert-cyclobutanols efficiently through enantioselective insertion into a C-C σ bond of the cyclobutane (see scheme; cod = 1,5-cyclooctadiene, DTBM = 3,5-di-tert-butyl-4-methoxyphenyl). Ring expansion by this method produced cyclohexenones with quaternary stereogenic centers with excellent enantioselectivity. The catalyst loading can be decreased to just 0.1 mol% in rhodium.

ENANTIOTOPOSELECTIVE PLE-CATALYZED HYDROLYSIS OF CIS-5-SUBSTITUTED-1,3-DIACYLOXYCYCLOHEXANES. PREPARATION OF SOME USEFUL CHIRAL BUILDING BLOCKS

PLE-catalyzed hydrolysis of prochiral cis-5-benzyloxymethyl-1,3-diacetoxycyclohexane and cis-5-benzyloxy-1,3-diacetoxycyclohexane proceeds with high enantiotoposelectivity.The preparation of some useful chiral building blocks is described.