130256-40-5Relevant academic research and scientific papers
Total syntheses of (-)-huperzine Q and (+)-lycopladines B and C
Hong, Benke,Li, Houhua,Wu, Jinbao,Zhang, Jing,Lei, Xiaoguang
, p. 1011 - 1015 (2015)
Utilizing a late-stage enamine bromofunctionalization strategy, the twelve-step total synthesis of (-)-huperzine Q was accomplished. Furthermore, the first total syntheses of (+)-lycopladines B and C are described. An unprecedented X-ray crystal structure
Divergent Total Syntheses of (?)-Huperzine Q, (+)-Lycopladine B, (+)-Lycopladine C, and (?)-4-epi-Lycopladine D
Hong, Benke,Hu, Dachao,Wu, Jinbao,Zhang, Jing,Li, Houhua,Pan, Yingming,Lei, Xiaoguang
supporting information, p. 1557 - 1567 (2017/07/11)
We report herein our synthetic efforts towards the divergent syntheses of (?)-huperzine Q (1), (+)-lycopladine B (2), (+)-lycopladine C (3), and (?)-lycopladine D (4). The 10-step total synthesis of (?)-huperzine Q (1) and the first total syntheses of (+)
Revision of the enantiotoposelective PLE-catalyzed hydrolysis of cis-5-substituted-1,3-diacyloxycyclohexanes
Dumortier, L.,Carda, M.,Eycken, J. Van der,Snatzke, G.,Vandewalle, M.
, p. 789 - 792 (2007/10/02)
Revision of previous work shows that PLE-catalyzed hydrolysis of 1 leads to the (S)-alcohol 5 and not the (R)-alcohol 3.However the homologue 2 gives the (R)-alcohol 4.
Synthetic studies towards the immunosuppressant FK-506 synthesis of the C10-C34 fragment
Wang, Zhaoyin
, p. 4631 - 4634 (2007/10/02)
The synthesis of the cyclohexyl moiety of FK-506 and its coupling reaction with the C10-C26 fragment to provide an advanced synthetic intermediate(C10-C34) are described.
ENANTIOTOPOSELECTIVE PLE-CATALYZED HYDROLYSIS OF CIS-5-SUBSTITUTED-1,3-DIACYLOXYCYCLOHEXANES. PREPARATION OF SOME USEFUL CHIRAL BUILDING BLOCKS
Carda, M.,Eycken, J. Van der,Vandewalle, M.
, p. 17 - 20 (2007/10/02)
PLE-catalyzed hydrolysis of prochiral cis-5-benzyloxymethyl-1,3-diacetoxycyclohexane and cis-5-benzyloxy-1,3-diacetoxycyclohexane proceeds with high enantiotoposelectivity.The preparation of some useful chiral building blocks is described.
