13027-13-9

Upstream product

• 84056-92-8 N₃-cyclohexyl-N₁-(2-hydroxyethyl)-N₁-nitrosothiourea 
• 107-21-1 ethylene glycol 
• 2387-23-7 1,3-Dicyclohexylurea 
• 96-49-1 [1,3]-dioxolan-2-one 
• 62-53-3 aniline 
• 108-91-8 cyclohexylamine 
• 3173-53-3 Cyclohexyl isocyanate 
• 76310-06-0 2-(cyclohexylimino)-3-nitroso-2-oxazolidine 

Downstream Products

• 107-21-1 ethylene glycol 
• 2387-23-7 1,3-Dicyclohexylurea 
• 31502-57-5 2-chloroethyl N-cyclohexylcarbamate 

Relevant academic research and scientific papers

Substituted pyrimidinetrione compound, composition containing same and application of substituted pyrimidinetrione compound

The invention provides a substituted pyrimidinetrione compound, a composition containing the same and application of the substituted pyrimidinetrione compound. The invention discloses the pyrimidinetrione compound as shown in formula (I) or the crystal form, pharmaceutically acceptable salt, prodrug, stereisomer, hydrate or solvent compound thereof. The pyrimidinetrione compound and the composition containing the same can be used for regulating hypoxia-inducible factors (HIF) and/or erythropoietin (EPO) and can be used for preparing medicine for regulating and controlling human body anemia.

Ruthenium-Na2CO3-catalyzed one-pot synthesis of ring-hydrogenated carbamates from aromatic amines and organic carbonates under H2

A facile and efficient one-pot procedure for the synthesis of ring hydrogenated carbamates from aromatic amine and alkylene carbonate under H2 gas pressure has been developed using a heterogeneous catalyst system comprising ruthenium and alkali metal carbonates. The effects of temperature, H2 pressure, catalyst (types of loaded metal and their supports), molar ratio of substrate/catalyst, and solvent were also investigated. Among the alkali metal carbonates, the sodium carbonate was found as best promoter for nucleophilic attack and ring-opening (NARO) reaction and thus increased the yield of ring hydrogenated carbamate up to 88% when using Ru/C as ring hydrogenation (RH) catalyst. This catalyst system could be reused at least five times without signi?cant loss of activity, which makes this process cost-effective and eco-friendly.

Organocatalyzed synthesis of ureas from amines and ethylene carbonate

A new solventless method for the synthesis of symmetrical and unsymmetrical ureas, starting from ethylene carbonate and amines, is reported. 1,5,7-Triazabicyclo[4.4.0]dec-5-ene(TBD) and thioureas have been found to be efficient organocatalysts for this reaction.

Enzymatic production of (meth)acrylic esters that contain urethane groups

Enzymatic preparation of (meth)acrylic esters containing urethane groups, and their use in radiation-curable compositions.

Synthesis of β-amino alcohols from aromatic amines and alkylene carbonates using Na-Y zeolite catalyst

A simple, efficient, and environmentally benign methodology for the synthesis of β-amino alcohols from aromatic amines and alkylene carbonates in the presence of the highly active and reusable solid base catalyst Na-Y zeolite is demonstrated. Georg Thieme Verlag Stuttgart.

REACTION OF ORGANIC CARBONATES WITH AMINES. III. REACTION OF AMINES WITH ALKYLENE CARBONATES

Urethano alcohols were synthesized by reaction of amines with cyclic alkylene carbonates containing an ether group, and the kinetics of the reaction were studied.In aprotic solvents the reaction has second order and is accelerated with increase in the pol