130272-30-9

Upstream product

• 16251-45-9 (4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one 
• 102-92-1 Cinnamoyl chloride 
• 492-41-1 (1R,2S)-norephedrine 
• 191043-26-2 (4S,5R)-4-methyl-5-phenyl-1,3-oxazolidine-2-thione 
• 599164-43-9 (4S,5R)-4-methyl-5-phenyl-3-[(E)-phenylprop-2-enoyl]-1,3-oxazolidine-2-thione 

Downstream Products

• 130178-08-4 (4S,5R)-3-(2,5-Dimethyl-6-phenyl-cyclohex-3-enecarbonyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 130178-11-9 2,5-Dimethyl-6-phenyl-cyclohex-3-enecarbothioic acid S-benzyl ester 
• 130178-09-5 2,5-Dimethyl-6-phenyl-cyclohex-3-enecarboxylic acid ((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-amide 
• 147599-28-8 4-((2R,3R)-5-oxo-3-phenyltetrahydrofuran-2-yl)benzonitrile 

Relevant academic research and scientific papers

Stereoselective conjugate radical additions: Application of a fluorous oxazolidinone chiral auxiliary for efficient tin removal

(Chemical Equation Presented) A series of asymmetric free-radical-mediated intermolecular conjugate additions using a fluorous oxazolidinone chiral auxiliary has been completed. The fluorous auxiliary facilitated product isolation using fluorous solid phase extractions (FSPE), effectively removing excess organic and organometallic reagents. Parallel reactions carried out with a similar but nonfluorous norephedrine-derived oxazolidinone demonstrated the superior stereoselectivity and purification obtainable with the fluorous chiral auxiliary.

(S)-4-Isopropyl-5,5-dimethyl-1,3-oxazolidinethione as chiral auxiliary for the intramolecular sulfur transfer in α,β-unsaturated N-acylimides, promoted by NbCl5

The 1,3-oxazolidinethione 4 has been synthesized from (S)-valine and used in the intramolecular sulfur transfer in its N-enoyl derivatives in the presence of NbCl5 as catalyst, which, moreover, works as an indicator of the course of the reactio