130284-41-2

Upstream product

• 137172-33-9 3-(2,2,4-trimethyl-1,3-dioxolan-4-yl)propanal 
• 57624-96-1 3-(2,2,4-trimethyl-[1,3]dioxolan-4-yl)-propan-1-ol 
• 130284-39-8 3-tert-butyldiphenylsilyloxy-1-(2,2,4-trimethyl-1,3-dioxolan-4-yl)hex-5-yne 
• 130284-40-1 5-tert-butyldiphenylsilyloxy-2-methyloct-7-yne-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 130284-45-6 4-(1,7-dioxaspiro<5.5>undec-4-en-2-yl)-2-hydroxy-2-methylbutyl toluene-p-sulphonate 
• 130284-44-5 2,5-dihydroxy-2-methyl-8-(tetrahydro-2-methoxypyran-2-yl)oct-7-yn-1-yl toluene-p-sulphonate 
• 130284-43-4 2-methyl-2,5-bis(trimethylsilyloxy)oct-7-yn-1-yl toluene-p-sulphonate 
• 130284-42-3 2,5-dihydroxy-2-methyloct-7-yn-1-yl toluene-p-sulphonate 

Relevant academic research and scientific papers

Chemistry of Bis-spiroacetals: Synthesis of cis- and trans-1-(2-Methyl-1,6,8-trioxadispiropentadec-13-en-2-yl)methanol

The synthesis of the cis and trans isomers of the bis-spiroacetal 25 is described, establishing methodology for the preparation of the polyether antibiotic epi-17-deoxy-(O-8)-salinomycin 3.The hydroxymethyl group at C-2 of 25, which provides an important

Synthesis of a functionalised bisspiroacetal

The synthesis of bis-spiroacetal (15) bearing an hydroxymethyl group at C-2 is described establishing a methodology for preparation of the polyether antibiotics salinomycin and narasin. Formation of an important iodohydrin intermediate has been accomplish