130291-54-2

Upstream product

• 23438-61-1 1-(toluene-4-sulfonyl)piperidin-2-one 
• 130291-49-5 2-(tert-Butoxycarbonyl-methyl-amino)-3-[2-oxo-3-phenylsulfanyl-1-(toluene-4-sulfonyl)-piperidin-3-yl]-propionic acid methyl ester 
• 143076-20-4 N-(p-Toluenesulfonyl)-3-(phenylthio)-2-piperidone 
• 56776-34-2 N-Boc-N-methyl-dehydroalanine methyl ester 
• 55477-80-0 methyl 2-[(tert-butoxycarbonyl)amino]acrylate 
• 69942-12-7 N-tert-butoxycarbonylserine methyl ester 
• 54125-02-9 danishefsky's diene 
• 130291-51-9 3-<2-(Methoxycarbonyl)-2-ethyl>-2-(p-toluenesulfonyl)-5,6-dihydro-2(1H)-pyridinone 

Downstream Products

• 143076-18-0 rac-Methyl (2R^*,3aS^*,6aS^*,10aS^*)-3-methyl-5,10-dioxo-9-(p-toluenesulfonyl)-1,2,3,3a,4,5,6,6a,7,8,9,10-dodecahydropyrrolo<2,3-i>isoquinoline-2-carboxylate 5-ethylene ketal 
• 143167-08-2 rac-Methyl (2S^*,3aS^*,6aS^*,10aS^*)-3-methyl-5,10-dioxo-9-(p-toluenesulfonyl)-1,2,3,3a,4,5,6,6a,7,8,9,10-dodecahydropyrrolo<2,3-i>isoquinoline-2-carboxylate 
• 143167-09-3 rac-Methyl (2R^*,3aS^*,6aS^*,10aS^*)-3-methyl-5,10-dioxo-9-(p-toluenesulfonyl)-1,2,3,3a,4,5,6,6a,7,8,9,10-dodecahydropyrrolo<2,3-i>isoquinoline-2-carboxylate 

Relevant academic research and scientific papers

SYNTHETIC STUDIES ON MANZAMINE A II; A NOVEL DIELS-ALDER APPROACH TO THE PYRROLOISOQUINOLINE SKELETON

An expeditious preparation of the central pyrroloisoquinoline skeleton of manzamine A (1) was achieved via the high-pressure Diels-Alder reaction of 3-alkyl-5,6-dihydro-2-pyridinone (10) with Danishefsky diene followed by deprotection and spontaneous pyrr