130293-13-9Relevant academic research and scientific papers
Pd-catalyzed regio- and stereoselective addition of boronic acids to silylacetylenes: A stereodivergent assembly of β,β-disubstituted alkenylsilanes and alkenyl halides
Kong, Wei,Che, Chao,Wu, Jialin,Ma, Liai,Zhu, Gangguo
, p. 5799 - 5805 (2014/07/08)
An efficient Pd-catalyzed addition of boronic acids to silylacetylenes is described, providing β,β-disubstituted (E)- or (Z)-alkenylsilanes in satisfactory yields with excellent regio- and stereoselectivity under mild reaction conditions. It represents the first highly regio- and stereoselective addition of boronic acids to aryl and alkenyl silylacetylenes. Moreover, the sequential Pd-catalyzed boron addition/N-halosuccinimide-mediated halodesilylation reaction results in a stereodivergent approach to β,β-disubstituted alkenyl halides, which can serve as versatile synthetic intermediates for the stereodivergent assembly of (E)- and (Z)-trisubstituted alkenes via transition-metal-catalyzed cross-coupling reactions.
IODO-CARBOFUNCTIONALIZATION OF ALKYNES WITH AROMATIC RINGS AND IPy2BF4
Barluenga, Jose,Rodriguez, Miguel A.,Gonzalez, Jose M,Campos, Pedro J.
, p. 4207 - 4210 (2007/10/02)
Alkynes react with bis(pyridine)iodine(I)tetrafluoroborate (1) and aromatic rings (activated, nonactivated and deactivated) in a Friedel-Crafts-type alkylation reaction to give, in a regio- and stereoselective way, trans-β-iodostyrene derivatives.
