130306-76-2

Upstream product

• 852395-08-5 [3-({4-[(3-aminopropyl)-tert-butyloxycarbonylamino]butyl}-tert-butyloxycarbonylamino)propyl]carbamic acid 2-(trimethylsilyl)ethyl ester 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 105751-14-2 N^α-Fmoc-Tyr-OPfp 
• 172992-43-7 pentafluorophenyl butanoate 
• 177213-61-5 di-tert-butyl butane-1,4-diylbis((3-aminopropyl)carbamate) 
• 181524-53-8 (S)-2-Amino-3-(4-benzyloxy-phenyl)-propionic acid 4-nitro-phenyl ester 
• 13512-59-9 N-(tert-butyloxycarbonyl)-O-(phenylmethyl)-L-tyrosine 4-nitrophenol ester 
• 2130-96-3 O-benzyl-N-tert-butoxycarbonyl-L-tyrosine 
• 130203-14-4 N-Butyryl-O-benzyl-L-tyrosine-spermineamide 
• 134419-04-8 O-benzyl-PhTX-343-N_β,N_ε-di-Cbz-L-lysine amide 
• 21160-82-7 4-nitrophenyl N₂,N₆-bis[(phenylmethoxy)carbonyl]-L-lysinate 

Downstream Products

• 126890-98-0 <127I2>PhTX-343-L-lysine 

Relevant academic research and scientific papers

Side-chain-anchored Nα-Fmoc-Tyr-OPfp for bidirectional solid-phase synthesis

(Chemical Equation Presented) A mild resin-immobilization strategy employing a readily prepared trityl bromide resin for anchoring building blocks via a phenol group has been developed. With Nα-Fmoc-Tyr-OPfp as a starter building block, it was possible to prepare asymmetrically substituted hybrids of spider-and wasp-type polyamine toxins using solid-phase peptide synthesis conditions.

Synthesis and binding of [125I2]philanthotoxin-343, [125I2]philanthotoxin-343-lysine, and [125I2]philanthotoxin-343-arginine to rat brain membranes

125I2-iodinated philanthotoxin-343 (PhTX-343) (10), [125I2]PhTX-343-arginine (11), and [125I2]PhTX-343-lysine (12) were synthesized and evaluated as probes for glutamate receptors in rat br