13033-50-6Relevant academic research and scientific papers
Bismuth-catalyzed synthesis of polycyclic aromatic hydrocarbons (PAHs) with a phenanthrene backbone via cyclization and aromatization of 2-(2-arylphenyl)vinyl ethers
Murai, Masahito,Hosokawa, Naoki,Roy, David,Takai, Kazuhiko
, p. 4134 - 4137 (2014)
The reaction of 2-(2-arylphenyl)vinyl ethers in the presence of a catalytic amount of bismuth(III) triflate gave substituted phenanthrenes in excellent yields under mild reaction conditions. The reaction was also applied to the construction of other polycyclic aromatic hydrocarbons (PAHs), such as chrysene, helicene, and pyrene having a phenanthrene backbone, via regioselective cyclization. This method has the advantages of easy availability of the cyclization precursors, operational simplicity, and high reaction efficiency.
Cobalt-Catalyzed α-Arylation of Substituted α-Halogeno β-Lactams
Koch, Vanessa,Lorion, Mélanie M.,Barde, Etienne,Br?se, Stefan,Cossy, Janine
supporting information, p. 6241 - 6244 (2019/08/26)
The treatment of 3-bromo β-lactams by an aryl Grignard, in the presence of CoCl2 (2 mol %) and TMEDA (2 mol %) in THF, produces 3-aryl β-lactams in good yields and excellent diastereoselectivity.
Catalytic Asymmetric Synthesis of N-Chiral Amine Oxides
Bhadra, Sukalyan,Yamamoto, Hisashi
supporting information, p. 13043 - 13046 (2016/10/30)
Direct asymmetric synthesis of N-chiral amine oxides was accomplished (up to 91:9 e.r.) by means of a bimetallic titanium catalyst. A hydroxy group situated at the γ-position of the N stereocenter enables the desired N-oxidation through dynamic kinetic resolution of the trivalent amine substrates. The method was further extended to the kinetic resolution of racemic γ-amino alcohols with a preexisting stereocenter, giving an important class of enantioenriched (up to 99.9:0.1 e.r.) building blocks that are otherwise difficult to synthesize.
Reactions of Diene-conjugated 1,3-Dipolar Intermediates: A Versatile and Efficient Route to Dibenzazepines via Benzonitrile o-Arylbenzyl Ylides
Cullen, Kevin E.,Sharp, John T.
, p. 2961 - 2968 (2007/10/02)
Diene-conjugated nitrile ylides of the type 1 in which both the α,β- and the γ,δ-double bonds are aromatic and where R is either hydroger or a para substitutent, cyclise to give dibenzazepines21 (Scheme 2) in high yield.This is in contrast to the analogous diazo system 2 in which cyclisation do not occur.The presence of an ortho methyl group in the ring under attack (1j, Scheme 3) prevents cyclisation via its steric limitations of conjugation in the transition state.
