130351-55-2Relevant academic research and scientific papers
Syntheses and Biological Evaluations of 3'-Deoxy-3'-C-Branched-Chain-Substituted Nucleosides
Lin, Tai-Shun,Zhu, Ju-Liang,Dutschman, Ginger E.,Cheng, Yung-Chi,Prusoff, William H.
, p. 353 - 362 (2007/10/02)
Various 3'-deoxy-3'-C-(hydroxymethyl)-, 3'-deoxy-3'-C-(fluoromethyl)-, 3'-deoxy-3'-C-(azidomethyl)-, and 3'-deoxy-3'-C-(aminomethyl)-substituted nucleosides (total 12 compounds) have been synthesized and evaluated against L1210, P388, S-180, and CCRF-CEM
Synthesis of antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides
Bamford,Coe,Walker
, p. 2494 - 2501 (2007/10/02)
A series of 3'-branched-chain sugar nucleosides, in particular 3'-deoxy-3'-C-hydroxymethyl nucleosides, have been synthesized and evaluated as antiviral agents. Reaction of 1-(2,3-epoxy-5-O-trityl-β-D-lyxo-pentafuranosyl) derivatives 12 and 13, of uracil
