1303541-48-1Relevant articles and documents
Interaction of β-lactam carbenes with 3,6-diphenyltetrazines: A five-step cascade reaction for the direct construction of indeno[2,1-b]pyrrol-2- ones
Xing, Juan,Wang, Xiao-Rong,Yan, Cai-Xia,Cheng, Ying
experimental part, p. 4746 - 4752 (2011/07/09)
A study of the nucleophilic addition of β-lactam carbenes to 3,6-diphenyltetrazines is reported. Instead of the formation of pyrazole derivatives like most reactions between nucleophilic or ambiphilic carbenes and 3,6-disubstituted tetrazines, β-lactam carbenes reacted with 3,6-diphenyltetrazines to produce indeno[2,1-b]pyrrol-2-ones in good yields. The reaction proceeds most probably through a five-step cascade process. This work has not only provided a one-pot operation for the efficient construction of mutisubstituted indeno[2,1-b]pyrrol-2-ones but also revealed the nucleophilicity of β-lactam carbenes.