1303573-48-9Relevant academic research and scientific papers
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation
Granchi, Carlotta,Roy, Sarabindu,De Simone, Alessio,Salvetti, Irene,Tuccinardi, Tiziano,Martinelli, Adriano,MacChia, Marco,Lanza, Mario,Betti, Laura,Giannaccini, Gino,Lucacchini, Antonio,Giovannetti, Elisa,Sciarrillo, Rocco,Peters, Godefridus J.,Minutolo, Filippo
supporting information; experimental part, p. 5398 - 5407 (2011/12/14)
Current cancer research is being increasingly focused on the study of distinctive characters of tumour metabolism, resulting in a switch from oxidative phosphorylation to glycolysis (Warburg effect). Isoform 5 of human lactate dehydrogenase (hLDH5), which
