33070-32-5

Usage

Uses

Used in Organic Synthesis:
5-Bromo-2,2-difluorobenzodioxole is used as a precursor in organic synthesis, providing a foundation for the creation of more complex molecules and compounds. Its unique structure allows for further functionalization and modification, making it a valuable component in the synthesis of a wide range of organic compounds.
Used in Pharmaceutical Industry:
As an intermediate in active pharmaceutical ingredients, 5-Bromo-2,2-difluorobenzodioxole plays a crucial role in the development of new drugs and therapeutic agents. Its specific chemical properties enable the design and synthesis of novel pharmaceutical compounds with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
5-Bromo-2,2-difluorobenzodioxole also serves as an intermediate in the agrochemical field, contributing to the development of new pesticides, herbicides, and other agricultural chemicals. Its unique structure allows for the creation of compounds with enhanced efficacy and selectivity, improving crop protection and yield.
Used in Dye Industry:
In the dyestuff field, 5-Bromo-2,2-difluorobenzodioxole is utilized as an intermediate for the synthesis of various dyes and pigments. Its chemical properties enable the production of dyes with specific color characteristics, stability, and performance, catering to the diverse requirements of different industries such as textiles, plastics, and printing.
Overall, 5-Bromo-2,2-difluorobenzodioxole is a versatile and valuable compound with applications spanning across various industries, including pharmaceuticals, agrochemicals, and dyestuff. Its unique structure and properties make it an essential component in the development of new and innovative products.

InChI:InChI=1/C12H10FN/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9,14H

Upstream product

• 17345-77-6 1-bromo-3,4-dihydroxybenzene 
• 1583-59-1 2,2-difluoro-1,3-benzodioxole 
• 7439-89-6 iron 
• 663934-04-1 (7-bromo-2,2-difluoro-1,3-benzodioxol-4-yl)triethylsilane 
• 663934-00-7 (2,2-difluoro-1,3-benzodioxol-4-yl)triethylsilane 
• 663934-09-6 (6-bromo-2,2-difluoro-1,3-benzodioxol-4-yl)triethylsilane 

Downstream Products

• 503269-73-6 (2,2-difluoro-1,3-benzodioxol-5-yl)diphenylphosphane oxide 
• 494841-92-8 tert-butyl (5S,6R,7R)-(+)-5-(2,3-dihydrobenzo[b]furan-6-yl)-7-(2-hydroxymethyl-4-methoxyphenyl)-2-(N-isopropylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylate 
• 232954-22-2 (5S,6R,7R)-5-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-7-[2-(3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid 
• 721965-60-2 (5S,6R,7R)-(+)-7-(2-acetoxymethyl-4-methoxyphenyl)-6-tert-butoxycarbonyl-5-(2,3-dihydrobenzo[b]furan-6-yl)-2-(N-benzoyl-isopropylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine 

Relevant academic research and scientific papers

Deprotonation-Triggered Heavy-Halogen Migrations as a Key to the Structural Elaboration of 2,2 -Difluoro-1,3-benzodioxole

Although proton abstraction from the 4-position of 2,2-difluoro-1,3-benzodioxole occurs with exceptional ease, lithiation of the more-remote 5-position can only be brought about if no oxygen-adjacent site remains unoccupied. Thus, unlike 4-bromo-2,2-diflu

Fluorodesulfurization of Thionobenzodioxoles with Silver(I) Fluoride

Difluorobenzodioxole is an important functional group found in both pharmaceuticals and agrochemicals. The late-stage introduction of this functional group is challenged by typical fluorination conditions of HF and strong oxidants. Here, we demonstrate that a range of difluorobenzodioxoles can be prepared from catechols in two steps through conversion into thionobenzodioxoles, followed by desulfurative fluorination with silver(I) fluoride. These mild reaction conditions are compatible with a variety of functional groups and enable access to a range of functionalized difluorobenzodioxoles.

Synthesis method of (2,2-difluorobenzo[d][1,3]dioxy-5-yl)methanol

The invention discloses a preparation method of (2,2-difluorobenzo[d][1,3]dioxo-5-yl)methanol as a fine chemical intermediate. The method is simple and feasible, lower in cost, and suitable for preparing (2,2-difluorobenzo[d][1,3]dioxo-5-yl)methanol through industrial production.

PROCESS FOR THE PREPARATION OF DERIVATIVES OF BENZODIOXOLE

The present invention relates to the process for preparing compounds of Formula I, Formula III and Formula V.

PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF AROMATIC ETHERS

The present invention relates to the process for the preparation of halogenated derivatives of aromatic ethers.

Process for preparing 5-bromo-2,2-difluorobenzo-1,3-dioxoles

The invention relates to a process for preparing 5-bromo-2,2-difluorobenzo-1,3-dioxoles and to the use thereof for preparing medicaments and crop protection agents.

Process for the preparation of 5-bromo-2,2-difluorobenzo-(1,3)-dioxoles

Preparation of 5-bromo-2,2-difluoro-benzo[1,3]dioxole compounds (I) comprises reacting 2,2-difluoro-benzo[1,3]dioxole compounds (II) with bromine in the presence of at least two Friedel-Crafts catalysts, one of the catalyst being hydrogen fluoride. Preparation of 5-bromo-2,2-difluoro-benzo[1,3]dioxole compounds of formula (I) comprises reacting 2,2-difluoro-benzo[1,3]dioxole compounds of formula (II) with bromine in the presence of at least two Friedel-Crafts catalysts, one of the catalyst being hydrogen fluoride. R 1>1-4C alkyl, Br, Cl or F; and n : 0-1. [Image].

Herbicidal benzodioxoles and benzodioxanes

Compounds of Formula I, and their N-oxides and agriculturally-suitable salts, are disclosed which are useful for controlling undesired vegetation STR1 wherein: STR2 T is O or S; W is a single bond, O, S or NR6 ; X is N or CH; Y is N or CH; Z is

Benzoheterocyclyl ketone hydrazone insecticides

Benzoheterocyclyl ketone hydrazones of the formula STR1 in which Y is methylene, difluoromethylene or oxygen and n is 0 or 1, compositions thereof and their use as insecticides are disclosed and exemplified.