130372-43-9

Upstream product

• 102208-55-9 2,5-anhydro-3,4,6-tri-O-benzyl-D-mannitol 
• 108-24-7 acetic anhydride 
• 102292-67-1 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-diethoxyphophinoyl-D-mannitol 
• 41107-82-8 2,5-anhydro-D-mannitol 
• 109065-80-7 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-iodo-D-mannitol 
• 68774-48-1 2,5-anhydro-1-O-trityl-D-mannitol 

Downstream Products

• 130466-42-1 2,5-anhydro-3,4-di-O-benzyl-1-deoxy-1-diethylphosphono-6-O-diphenylphosphono-D-mannitol 
• 130465-01-9 ((2S,3S,4R,5R)-3,4-Bis-benzyloxy-5-hydroxymethyl-tetrahydro-furan-2-ylmethyl)-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Stereospecific synthesis of 5-phospho-α-D-arabinosyl-C-phosphonophosphate (pACpp): A stable analogue of the putative mycobacterial cell wall biosynthetic intermediate 5-phospho-D-arabinosyl pyrophosphate (pApp)

The stereospecific synthesis of 5-phospho-α-D-arabinosyl-C-phosphonophosphate (pACpp) from D-glucosamine is described. This compound was evaluated for its ability to serve as a stable analogue of the putative mycobacterial cell wall biosynthetic intermediate 5-phospho-D-arabinosyl pyrophosphate (pApp). The phosphonophosphate proved incapable of interfering with formation of the mycobacterial arabinan precursor decaprenylphospho-arabinose (DpA) in vitro.