13039-68-4Relevant academic research and scientific papers
A new approach to the synthesis of optically active alkylated adenine derivatives
Zakirova,Shipitsyn,Belanov,Jasko
, p. 3357 - 3360 (2004)
A new synthesis of chiral acyclic nucleoside and nucleotide analogues starting from D(-)- or L(+)-riboses was proposed. Antiviral properties of the synthesized compounds towards the pox virus family were evaluated.
Phosphorylated Glycoconjugates Based on Isosteviol, d-Arabinofuranose, and d-Ribofuranose
Sharipova,Belenok,Strobykina, I. Yu.,Kataev
, p. 508 - 513 (2019/06/05)
First phosphorylated glycoconjugates were synthesized in three stages on the basis of isosteviol, d-arabinofuranose, and d-ribofuranose. In the first stage, isosteviol reacted with methyl 5-O-(p-tosyl)-2,3-di-O-benzoyl-d-ribofuranoside and methyl 5-O-(p-tosyl)-2,3-di-O-benzoyl-d-arabinofuranoside to give glycoconjugates in which the diterpenoid fragment is linked through ester bond to the carbohydrate C5 atom. In the second stage, the anomeric methoxy group in the furanoside fragment was replaced by bromine, and the resulting 2,3-di-O-benzoyl-d-ribofuranosyl and 2,3-di-O-benzoyl-d-arabinofuranosyl bromides were treated with dibutyl phosphate to afford the target phosphorylated derivatives.
SYNTHESIS OF NOVEL 3'-ISOMERIC DIDEOXYNUCLEOSIDES
Nuesca, Zoradia M.,Nair, Vasu
, p. 2485 - 2488 (2007/10/02)
Approaches to representative examples of 3'-isomeric dideoxynucleosides with 2'(S),3'(R) and 2'(R),3'(S) absolute stereochemistry have been developed.These are among the first cases of isomeric dideoxynucleosides with the base moiety at the 3'-position.The chemistry developed has generality and can be applied to the synthesis of other related isomeric nucleosides.
