13039-75-3 Usage
Description
5-Deoxy-D-ribose is a monosaccharide that is structurally similar to D-ribose but lacks an oxygen atom at the 5' position. It is an important intermediate in the synthesis of various nucleoside analogs and pharmaceutical compounds.
Used in Pharmaceutical Industry:
5-Deoxy-D-ribose is used as a key intermediate in the synthesis of Capecitabine, an oral chemotherapy drug used for the treatment of various types of cancer, including breast and colorectal cancer. It is also used in the preparation of β-trialkyl carbonate nucleosides, which have potential applications in the development of new antiviral and anticancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 13039-75-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,3 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13039-75:
(7*1)+(6*3)+(5*0)+(4*3)+(3*9)+(2*7)+(1*5)=83
83 % 10 = 3
So 13039-75-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O4/c1-3(7)5(9)4(8)2-6/h2-5,7-9H,1H3/t3-,4+,5-/m1/s1
13039-75-3Relevant articles and documents
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Collins
, p. 1960,1961,1964 (1971)
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SYNTHESIS AND N.M.R.-SPECTRAL ANALYSIS OF UNENRICHED AND -ENRICHED 5-DEOXYPENTOSES AND 5-O-METHYLPENTOSES
Snyder. Joseph R.,Serianni, Anthony S.
, p. 169 - 188 (2007/10/02)
Chemical methods are described for preparing unenriched and -enriched 5-deoxy- and 5-O-methyl-pentoses in the D or L configuration.The 1H-n.m.r.-spectra of these compounds have been interpreted, and the 13C n.m.r. spectra assigned with the aid of 2-D 13C-1H chemical-shift correlation spectroscopy.Tautomeric forms (furanoses, hydrate, and aldehyde) in solution in 2H2O have been quantified with the aid of -enriched derivatives.Spectra of 5-deoxypentoses, and methyl pentofuranosides have been compared, in order to assess the effect of 5-C-deoxygenation and 5-O-methylation on chemical shifts and coupling constants (1H-1H, 13C-1H, and 13C-13C) and on the pentofuranose conformations.