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4137-56-8

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  • Factory Price API 99% Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-beta-D-ribofuranoside 4137-56-8 GMP Manufacturer

    Cas No: 4137-56-8

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4137-56-8 Usage

Chemical Properties

Crystalline Solid

Uses

Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl-?-D-ribofuranoside (cas# 4137-56-8) is a compound useful in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 4137-56-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,3 and 7 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4137-56:
(6*4)+(5*1)+(4*3)+(3*7)+(2*5)+(1*6)=78
78 % 10 = 8
So 4137-56-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H22O7S/c1-10-5-7-11(8-6-10)24(17,18)20-9-12-13-14(15(19-4)21-12)23-16(2,3)22-13/h5-8,12-15H,9H2,1-4H3/t12-,13-,14-,15-/m1/s1

4137-56-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl-?-D-ribofuranoside

1.2 Other means of identification

Product number -
Other names Methyl 2,3-O-isopropylidene-5-O-(p-tolylsulfonyl)-β-D-ribofuranoside

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4137-56-8 SDS

4137-56-8Downstream Products

4137-56-8Relevant articles and documents

[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging

Li, Xiang-Guo,Dall'Angelo, Sergio,Schweiger, Lutz F.,Zanda, Matteo,O'Hagan, David

, p. 5247 - 5249 (2012)

[18F]-5-Fluoro-5-deoxyribose ([18F]-FDR) conjugates much more rapidly than [18F]-FDG under mild reaction conditions to peptides and offers new prospects for mild and rapid bioconjugation for fluorine-18 labelling in PET imaging.

A facile ultrasound-assisted synthesis of methyl 2,3-O-isopropylidene-β-D-ribofuranoside from D-ribose and its use to prepare new 1,2,3-triazole glycoconjugates

Evangelista, Tereza Cristina Santos,Aquino, Gabriel Alves Souto de,Donza, Marcio Roberto H.,Leit?o, Rafael Lisboa,Carvalho, Victor Salarolli de,Kaiser, Carlos Roland,Ferreira, Sabrina Baptista

, p. 243 - 268 (2021/10/23)

The conversion of D-ribose into its 2,3-O-isopropylidene derivative using ultrasonic irradiation is described. The ultrasound proved to be an excellent alternative as the energy source for the reaction. Different reaction times were investigated, and shorter reaction times and high yield were achieved without the need for purification of the acetonide. The compound was then applied as the starting material in the synthesis of 23 new glycoconjugates of 1,2,3-triazole that are tethered together in different ways. The synthesized compounds were characterized by FTIR, 1H NMR, 13C NMR, and HRMS techniques.

Synthesis and biological evaluation of benzo[f]indole-4,9-diones n-linked to carbohydrate chains as new type of antitumor agents

Dias, Flaviana R.F.,Guerra, Fabiana S.,Lima, Fernanda A.,de Castro, Yasmin K.C.,Ferreira, Vitor F.,Campos, Vinícius R.,Fernandes, Patrícia D.,Cunha, Anna C.

, p. 476 - 489 (2021/02/12)

In this work, we report the synthesis of three series of carbohydrate-based benzo[f]indole-4,9-diones and amino-1,4-naphthoquinone derivatives and evaluated their cytotoxic activity against eight human cancer cell lines. Several compounds showed a promising cytotoxic activity toward the tumor cell lines (half maximal inhibitory concentration (IC50) 10.0 μM). The importance of the substitution pattern of the quinone derivatives on the antitumor activity was also discussed. 3-Carboethoxy-2-methyl-benzo[f]indole-4,9-dione derivatives were more cytotoxic than their parent compounds and amino-1,4-naphthoquinones. Unlike clinically useful anticancer agent doxorubicin, the majority of synthesized compounds did not exhibit any lytic effects against erythrocytes or normal human leukocytes.

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