130405-91-3

Upstream product

• 130405-90-2 N₃-Z-N₄-Boc-(S)-CDAPA-Leu pyridin-2-ylmethylamide 
• 130405-85-5 (3S,4S)-3-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-5-cyclohexyl-pentanoic acid ethyl ester 
• 130405-89-9 N₃-Z-N₄-Boc-(3S,4S)-5-cyclohexyl-3,4-diaminopentanoic acid 
• 110696-06-5 (S)-2-Amino-4-methyl-pentanoic acid (pyridin-2-ylmethyl)-amide; hydrochloride 
• 114371-49-2 ethyl -5-cyclohexyl-4-<<(1,1-dimethylethoxy)carbonyl>amino>-2-pentenoate 
• 146136-24-5 (S)-3-Amino-4-tert-butoxycarbonylamino-5-cyclohexyl-pentanoic acid ethyl ester 
• 98105-42-1 (S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-1-propanal 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 147933-37-7 sodium 2-[8-isobutyl-6-phenyl-1,2,4-triazolo[4,3-a]pyrazin-3-yl]-3-(pyridin-3-yl)propanoate 
• 130405-86-6 (3R,4S)-3-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-5-cyclohexyl-pentanoic acid ethyl ester 
• 130405-89-9 N₃-Z-N₄-Boc-(3R,4S)-5-cyclohexyl-3,4-diaminopentanoic acid 

Downstream Products

• 130405-96-8 N₄-<(2S)-2-(8-Isobutyl-6-phenyl-1,2,4-triazolo<4,3-a>pyrazin-3-yl)-3-pyridin-3-ylpropanoyl>-(S)-CDAPA-Leu pyridin-2-ylmethylamide 
• 130405-96-8 N₄-<(2R)-2-(8-isobutyl-6-phenyl-1,2,4-triazolo<4,3-a>pyrazin-3-yl)-3-pyridin-3-ylpropanoyl>-(S)-CDAPA-Leu pyridin-2-ylmethylamide 
• 130405-96-8 (3R,4S)-3-Amino-5-cyclohexyl-4-[(S)-2-(8-isobutyl-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-yl-propionylamino]-pentanoic acid {(S)-3-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 130405-96-8 (3R,4S)-3-Amino-5-cyclohexyl-4-[(R)-2-(8-isobutyl-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-3-pyridin-3-yl-propionylamino]-pentanoic acid {(S)-3-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 

Relevant academic research and scientific papers

1,2,4-Triazolopyrazine Derivatives with Human Renin Inhibitory Activity. 3. Synthesis and Biological Properties of Aminodeoxystatine and Difluorostatone Derivatives

Two series of 1,2,4-triazolopyrazine derivatives with human renin inhibitory activity have been synthesized which incorporate the transition-state mimetics (3S,4S)- and (3R,4S)-5-cyclohexyl-3,4-diaminopentanoic acid ((S)- and (R)-CDAPA), and (4S)-4