1304062-29-0

Basic information

• Product Name: C₂₃H₂₈F₃N₃O₄
• CAS NO: 1304062-29-0
• Molecular Weight: 467.488
• Mol File: 1304062-29-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₈F₃N₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₈F₃N₃O₄(1304062-29-0)
• EPA Substance Registry System: C₂₃H₂₈F₃N₃O₄(1304062-29-0)

Safety Data

• Hazardous Substances Data: 1304062-29-0(Hazardous Substances Data)

Upstream product

• 854015-40-0 4-methyl-5-(4-trifluoromethyl phenyl)-isoxazole-3-carboxylic acid ethyl ester 
• 1237714-73-6 ethyl 4-(bromomethyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxylate 
• 1237714-78-1 4-(hydroxymethyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carboxylic acid 
• 1292902-59-0 C₅H₁₁NO 
• 1304062-21-2 C₁₈H₁₈ClF₃N₂O₃ 
• 1237714-83-8 4-(chloromethyl)-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carbonyl chloride 

Relevant articles and documents

Identification of potent, soluble, and orally active TRPV1 antagonists

Optimization of a water soluble, moderately potent lead series of isoxazole-3-carboxamides was conducted, affording a compound with the requisite balance of potency, solubility and physicochemical properties for in vivo use. Compound 8e was demonstrated to be efficacious in a rat model of inflammatory pain, following oral administration.