130408-07-0

Basic information

• Product Name: 2-benzyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one
• Synonyms: 2-benzyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one
• CAS NO: 130408-07-0
• Molecular Weight: 310.743
• Mol File: 130408-07-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-benzyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one(130408-07-0)
• EPA Substance Registry System: 2-benzyl-9-chloro-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one(130408-07-0)

Safety Data

• Hazardous Substances Data: 130408-07-0(Hazardous Substances Data)

Upstream product

• 5922-60-1 2-amino-5-chlorobenzonitrile 
• 104615-85-2 5-chloro-2-<(methoxycarbonyl)amino>benzonitrile 
• 937-39-3 2-phenylacetylhydrazine 
• 64411-72-9 5-chloro-2-isocyanatobenzonitrile 

Downstream Products

• 1217302-01-6 2-Benzyl-9-chloro-5-(4-methylpiperazin-1-yl)-[1,2,4]triazolo[1,5-c]quinazoline 
• 1217302-02-7 2-benzyl-5,9-dichloro-[1,2,4]triazolo[1,5-c]quinazoline 

Relevant articles and documents

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

Synthesis and Benzodiazepine Binding Activity of a Series of Novel Triazoloquinazolin-5(6H)-ones

Investigation of tricyclic heterocycles related to the 2-arylpyrazoloquinolin-3(5H)-ones, structures with high affinity for the benzodiazepine (BZ) receptor, led to the synthesis of 2-phenyl-triazoloquinazolin-5(6H)-one, a compound wi