130408-15-0

Basic information

• Product Name: 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID
• Synonyms: 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID;2,5-Difluoro-benzenepropanoic acid;3-(2,5-Difluorophenyl)propionic acid, 2,5-Difluorohydrocinnamic acid
• CAS NO: 130408-15-0
• Molecular Formula: C₉H₈F₂O₂
• Molecular Weight: 186.16
• Mol File: 130408-15-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 269.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.312±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.57±0.10(Predicted)
• CAS DataBase Reference: 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID(130408-15-0)
• EPA Substance Registry System: 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID(130408-15-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 130408-15-0(Hazardous Substances Data)

Usage

Description

3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID is a chemical compound that belongs to the propionic acid class of organic compounds. It is characterized by a propionic acid moiety with a 2,5-difluorophenyl group attached to the third carbon. 3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID is known for its potential applications in the pharmaceutical and chemical industries due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID is used as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new drug candidates with potential therapeutic benefits.
Used in Organic Synthesis:
3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID is used as a building block in the synthesis of various organic compounds. Its versatile structure enables the creation of a wide range of molecules with different functional groups and properties.
Used in Research and Development:
3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID is used as a valuable tool for research and development in the pharmaceutical and chemical industries. Its unique properties and potential applications make it an important compound for exploring new drug targets and developing innovative chemical processes.
Used in Anti-inflammatory and Analgesic Applications:
3-(2,5-DIFLUOROPHENYL)PROPIONIC ACID has been studied for its potential anti-inflammatory and analgesic properties. Its ability to modulate inflammatory pathways and alleviate pain makes it a promising candidate for the development of new therapeutic agents for the treatment of various inflammatory and painful conditions.

Upstream product

• 112898-33-6 3-(2,5-difluorophenyl)acrylic acid 

Downstream Products

• 1041481-56-4 N'-[3-(2,5-difluorophenyl)propionyl]-3-cyano-4-fluorobenzohydrazide 
• 130408-16-1 4,7-difluoro-1-indanone 

Relevant articles and documents

NON-NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS

Compounds of the formula Z: where; A is CH or N; R1 is a substituent to a carbon atom in the ring containing A selected from -S(=O)pRa, where Ra is -C1-C4 alkyl, -ORx, -NRxRx, -NHNRxRx, - NHNHC(=O)ORx, -NRxOH; -C(=O)-Rb, where Rb is -CT-C4-alkyl, ORx, -NRxRx, -NHNRxRx, -NHC1-C3-alkyl-C(=O)Orx -NRxRc, where Rc is H, C1-C4 alkyl, -NRxRx; -C(=0)Rd, -CN, S(=O)pRx where Rd is Rd is C1-C4-alkyl, -ORx, -NRxRx C1-C3-alkyl-O-Cl-C3alkylC(=O)ORx, -C1-C3-alkyl-COORx; -C1-C3alkyl-OH or C1-C4 alkyl ethers or esters thereof (O-Cl-C3alkyl)q-O-Rx a 5 or 6 membered aromatic ring having 1-3 hetero atoms p is 1 or 2; Rx is independently selected from H, C1-C4 alkyl or acetyl; or a pair of Rx can together with the adjacent N atom form a ring; L is -0-, -S(=O),- or -CH2-, where r is 0, 1 or 2; R3-R7 are substituents as defined in the specification; X is -(CR8R8')n-D-(CR8R8')m-; D is a bond, -NR9-, -0-, -S-, -S(=0)- or -S(=0)2-; and pharmaceutically acceptable salts and prodrugs thereof, have utility as HIV antivirals.