130435-35-7Relevant academic research and scientific papers
Fluoronaphthyridines and -quinolones as antibacterial agents. 3. Synthesis and structure-activity relationships of new 1-(1,1-dimethyl-2-fluoroethyl), 1-[1-methyl-1-(fluoromethyl)-2-fluoroethyl], and 1-[1,1-(difluoromethyl)-2-fluoroethyl] substituted deri
Remuzon,Bouzard,Di Cesare,Essiz,Jacquet,Kiechel,Ledoussal,Kessler,Fung-Tomc
, p. 29 - 37 (1991)
A series of novel N-1-(mono-, -(di- and -(trifluoro-tert-butyl) quinolones and -naphthyridines has been prepared. Structure-activity relationship (SAR) studies indicated that the in vitro antibacterial potency was the following order: 1-(1,1-dimethyl-2-fl
