Fluoronaphthyridines and -quinolones as antibacterial agents. 3. Synthesis and structure-activity relationships of new 1-(1,1-dimethyl-2-fluoroethyl), 1-[1-methyl-1-(fluoromethyl)-2-fluoroethyl], and 1-[1,1-(difluoromethyl)-2-fluoroethyl] substituted deri

DOI: 10.1021/jm00105a006

Source and publish data:

Journal of Medicinal Chemistry p. 29 - 37 (1991)

Update date:2022-08-02

Topics:

Authors:

Remuzon Remuzon

Bouzard Bouzard

Di Cesare

Essiz Essiz

Jacquet Jacquet

Kiechel Kiechel

Ledoussal

Kessler Kessler

Fung-Tomc

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00105a006

A series of novel N-1-(mono-, -(di- and -(trifluoro-tert-butyl) quinolones and -naphthyridines has been prepared. Structure-activity relationship (SAR) studies indicated that the in vitro antibacterial potency was the following order: 1-(1,1-dimethyl-2-fl

Full text of DOI:10.1021/jm00105a006

Products guided by the article

Product name:(Z)-2-(2-Chloro-4,5-difluoro-benzoyl)-3-(2-fluoro-1,1-bis-fluoromethyl-ethylamino)-acrylic acid ethyl ester

Cas No:130435-35-7

R&D Labs maybe for 130435-35-7

Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
qingdao goldenchem imp and exp co.,ltd.

Contact:532-55579246

Address:no.62 ,haier road laoshan distirct
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China

Relevant to this article

Doi:10.1021/jo01282a005
(1967)
Metal-Free Synthesis of 3-Arylquinolin-2-ones from Acrylic Amides via a Highly Regioselective 1,2-Aryl Migration: An Experimental and Computational Study

Doi:10.1021/acs.joc.6b00345
(2016)
Unusual reactions of amino acid derivatives: N-nitrooxazolidones and N-nitroamino acids

Doi:10.1021/ja00181a074
(1990)
Benzoquinone and naphthoquinone based redox-active labels for electrochemical detection of modified oligonucleotides on Au electrodes

Doi:10.1016/j.tetlet.2015.12.035
(2016)
Organophosphazenes. 25. The synthesis and electrochemistry of the dicobalt hexacarbonyl complexes of phenylethynylcyclophosphazenes

Doi:10.1139/v02-138
(2002)
Preparation of aliphatic ketones through a ruthenium-catalyzed tandem cross-metathesis/allylic alcohol isomerization

Doi:10.1021/ol060918g
(2006)

Article Doi