130457-20-4Relevant academic research and scientific papers
A PROGRAMMED FIVE-MEMBERED CYCLIC PHOSPHORYLATING REAGENT FOR THE SYNTHESIS OF OLIGONUCLEOTIDES AND ITS USE
Richter, Wolfgang,Karl, Rosmarie,Ugi, Ivar
, p. 3167 - 3172 (1990)
2-Chloro-2,4-dioxo-3-methyl-tetrahydro-1,3,2λ5-thiazaphosphole 1 is introduced as a programmed phosphorylating reagent for oligonucleotide syntheses.The homogeneous phase one-pot synthesis of a crystalline dithymidine derivative is described as an illustration of its application.
