1304581-64-3Relevant academic research and scientific papers
Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy
Evans, Karen A.,Shearer, Barry G.,Wisnoski, David D.,Shi, Dongchuan,Sparks, Steven M.,Sternbach, Daniel D.,Winegar, Deborah A.,Billin, Andrew N.,Britt, Christy,Way, James M.,Epperly, Andrea H.,Leesnitzer, Lisa M.,Merrihew, Raymond V.,Xu, Robert X.,Lambert, Millard H.,Jin, Jian
, p. 2345 - 2350 (2011/06/17)
A series of phenoxyacetic acids as subtype selective and potent hPPARδ partial agonists is described. Many analogues were readily accessible via a single solution-phase synthetic route which resulted in the rapid identification of key structure-activity r
