130464-40-3

Upstream product

• 112918-05-5 2-exo-(hydroxymethyl)-3-exo-<(phenylsulfonyl)amino>bicyclo<2.2.1>heptane 
• 130464-39-0 (1S,2S,3S,4R)-3-(Hydroxymethyl)-2-((phenylsulfonyl)amino)bicyclo<2.2.1>heptane 
• 132747-46-7 (1S,2S,3S,4R)-3-Carboxy-2-((phenylsulfonyl)amino)bicyclo<2.2.1>heptane 

Downstream Products

• 130464-41-4 N-[(1S,2S,3R,4R)-3-((E)-2-Methoxy-vinyl)-bicyclo[2.2.1]hept-2-yl]-benzenesulfonamide 
• 112966-96-8 Domitroban 
• 128299-81-0 (3'R,4'R,5'S,6'S)-5'-(Formylmethyl)-4'-benzenesulfonamidobicyclo<2.2.1>heptane 
• 112918-07-7 N-[(1S,2R,3R,4R)-3-((E)-2-Methoxy-vinyl)-bicyclo[2.2.1]hept-2-yl]-benzenesulfonamide 

Relevant academic research and scientific papers

Synthesis and in vitro activity of stereoisomers of a novel thromboxane receptor antagonist, (±)-(5Z)-7-[3-endo-[(phenylsulfonyl)amino]bicyclo[2.2.1]hept-2-exo-yl ]heptenoic acid

Three stereoisomers of S-145 (1) with variations at the side-chain junctions were synthesized. Endo-cis-isomer 10 and N-exo-trans isomer 18 were obtained via the common intermediate 5 having an endo-fused ring structure. Exo-cis isomer 28 was prepared via