1304775-59-4Relevant articles and documents
Substrate-controlled regioselective cobalt(I)-catalysed 1,4-hydrovinylation reactions
Hilt, Gerhard,Roesner, Stefan
, p. 662 - 668 (2011)
The substrate-directed regiochemistry of the cobalt-catalysed 1,4-hydrovinylation reaction is described. A variety of symmetrical and unsymmetrical 2,3-disubstituted 1,3-dienes are synthesised by ruthenium-catalysed enyne metathesis, and then reacted with a terminal alkene catalysed by cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane] [CoBr 2(dppe)] under reductive conditions. The regiochemistry of the branched 1,4-diene products is influenced by the nature of the substituents on the unsymmetrical 2,3-disubstituted 1,3-dienes. The influence of steric and electronic effects is also discussed. Georg Thieme Verlag Stuttgart New York.