1304777-34-1

Basic information

• Product Name: N-(4-BroMo-5-Methyl-2H-pyrazol-3-yl)-acetaMidine
• Synonyms: N-(4-BroMo-5-Methyl-2H-pyrazol-3-yl)-acetaMidine
• CAS NO: 1304777-34-1
• Molecular Formula: C6H9BrN4
• Molecular Weight: 217.06646
• Mol File: 1304777-34-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-BroMo-5-Methyl-2H-pyrazol-3-yl)-acetaMidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-BroMo-5-Methyl-2H-pyrazol-3-yl)-acetaMidine(1304777-34-1)
• EPA Substance Registry System: N-(4-BroMo-5-Methyl-2H-pyrazol-3-yl)-acetaMidine(1304777-34-1)

Safety Data

• Hazardous Substances Data: 1304777-34-1(Hazardous Substances Data)

Upstream product

• 1780-72-9 4-bromo-5-methyl-2H-pyrazol-3-ylamine 
• 1000-84-6 O-ethyl acetimidate 

Downstream Products

• 55457-59-5 8-bromo-2,7-dimethyl-3H-pyrazolo[1,5-a][1,3,5]triazin-4-one 

Relevant articles and documents

Potential CRF1R PET imaging agents: N-Fluoroalkyl-8-(6-methoxy- 2-methylpyridin-3-yl)-2,7-dimethyl-N-alkylpyrazolo[1,5-a][1,3,5]triazin-4-amines

A series of N-fluoroalkyl-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethyl- N-alkylpyrazolo[1,5-a][1,3,5]triazin-4-amines were prepared and evaluated as potential CRF1R PET imaging agents. Optimization of their CRF 1R binding potencies and octanol-phosphate buffer phase distribution coefficients resulted in discovery of analog 7e (IC50 = 6.5 nM, log D = 3.5).