1305173-66-3Relevant academic research and scientific papers
Synthesis of the stereogenic triad of the halicyclamine A core
Molander, Gary A.,Cadoret, Frédéric
, p. 2199 - 2202 (2011)
We describe herein our progress toward the synthesis of halicyclamine A, which possesses very interesting biological activities and has never been synthesized. For this purpose, we proposed a stereoselective Diels-Alder reaction as a key step for the establishment of the stereogenic triad of the bis(piperidinyl) core of this molecule. A series of NMR studies was then conducted to establish the correct stereochemical assignment subsequent to the Diels-Alder reaction.
